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KMID : 0383820100690010043
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Tuberculosis and Respiratory Diseases
2010 Volume.69 No. 1 p.43 ~ p.47
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Non-tuberculous Mycobacterial Lung Disease Presenting as a Solitary Pulmonary Nodule
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Kim Song-Yee
Park Moo-Suk
Kim Se-Kyu
Chang Joon
Kim Young-Sam
Lee Sang-Hoon
Park Byung-Hoon
Jung Ji-Ye
Son Ji-Young
Moon Jin-Wook
Shim Hyo-Sup
Lee Kyung-Jong
Yoon Yoe-Wun
Kang Young-Ae
Lee Sang-Kook
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Abstract
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We report a case of Mycobacterium intracellulare pulmonary infection presenting as a solitary pulmonary nodule (SPN). A 35-year-old male was admitted due to a SPN in the right upper lobe which was detected on the chest radiography being examed due to recurrent cough for 1 year. The computed tomography (CT) revealed a spiculated nodule containing air-bronchogram, which was suspicious of malignancy. We performed transbronchial biopsy and the pathology showed granulomatous inflammation with caseous necrosis. Under the presumptive diagnosis of pulmonary tuberculosis, we started anti-tuberculous medication including isoniazid, rifampin, ethambutol, and pyrazinamide. In one month, however, the sputum culture was positive for Mycobacterium intracellulare. The follow-up chest CT showed slight aggravation of the previous lesions. Under the final diagnosis of Mycobacterium intracellulare pulmonary infection presenting as a solitary pulmonary nodule, we changed the regimen to rifampin, ethambutol, and clarithromycin. The follow-up chest CT after the completion of treatment, revealed resolution of the previous lesions.
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KEYWORD
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Mycobacterium Infections, Atypical, Solitary Pulmonary Nodule, Tuberculosis
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